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CTLA4-Mediated Immunosuppression in Glioblastoma is Associated with the Infiltration of Macrophages in the Tumor Microenvironment

PURPOSE: CTLA4, the immune checkpoint, has been widely reported to contribute to immune evasion in anti-tumor activity. The inhibitors of CTLA4 provide a novel strategy to improve the outcome of peripheral cancer, but their clinical effects are limited in glioblastoma (GBM), thus the comprehensive r...

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Detalles Bibliográficos
Autores principales:	Guan, Xiudong, Wang, Yangyang, Sun, Yueqian, Zhang, Chuanbao, Ma, Shunchang, Zhang, Dainan, Li, Deling, Jia, Wang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8712744/ https://www.ncbi.nlm.nih.gov/pubmed/34992419 http://dx.doi.org/10.2147/JIR.S341981

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