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Exercise Reduces H3K9me3 and Regulates Brain Derived Neurotrophic Factor and GABRA2 in an Age Dependent Manner

Exercise improves cognition in the aging brain and is a key regulator of neuronal plasticity genes such as BDNF. However, the mechanism by which exercise modifies gene expression continues to be explored. The repressive histone modification H3K9me3 has been shown to impair cognition, reduce synaptic...

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Detalles Bibliográficos
Autores principales:	Ionescu-Tucker, Andra, Butler, Christopher W., Berchtold, Nicole C., Matheos, Dina P., Wood, Marcelo A., Cotman, Carl W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8712855/ https://www.ncbi.nlm.nih.gov/pubmed/34970138 http://dx.doi.org/10.3389/fnagi.2021.798297

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