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Dysregulated BMP2 in the Placenta May Contribute to Early-Onset Preeclampsia by Regulating Human Trophoblast Expression of Extracellular Matrix and Adhesion Molecules
Many pregnancy disorders, including early-onset preeclampsia (EOPE), are associated with defects in placental trophoblast cell invasion and differentiation during early placental development. Bone morphogenetic protein 2 (BMP2) belongs to the TGF-β superfamily and controls various physiological and...
Autores principales: | Yi, Yuyin, Zhu, Hua, Klausen, Christian, Chang, Hsun-Ming, Inkster, Amy M., Terry, Jefferson, Leung, Peter C. K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8712873/ https://www.ncbi.nlm.nih.gov/pubmed/34970543 http://dx.doi.org/10.3389/fcell.2021.768669 |
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