Cargando…

Genetic Alteration Profiling of Chinese Lung Adenocarcinoma and Its Effect on Targeted Therapy Efficacy

BACKGROUND: Non-small cell lung cancer (NSCLC) is the most common type of lung cancer and a highly heterogeneous disease with a diversity of phenotypes and genotypes in different populations. The purpose of this study is to investigate oncogenic alterations of lung adenocarcinoma (LUAD) in eastern C...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Jie, Xu, Wang-yang, Ye, Maosong, Liu, Zilong, Li, Chun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8712938/ https://www.ncbi.nlm.nih.gov/pubmed/34970478 http://dx.doi.org/10.3389/fonc.2021.726547

Ejemplares similares

Genomic Profiling and Prognostic Value Analysis of Genetic Alterations in Chinese Resected Lung Cancer With Invasive Mucinous Adenocarcinoma
por: Cai, Lei, et al.
Publicado: (2021)

Circulating Genetically Abnormal Cells Add Non-Invasive Diagnosis Value to Discriminate Lung Cancer in Patients With Pulmonary Nodules ≤10 mm
por: Ye, Maosong, et al.
Publicado: (2021)

Survival Benefit and Genetic Profile of Pemetrexed as Initial Chemotherapy in Selected Chinese Patients With Advanced Lung Adenocarcinoma
por: Guo, Long-Hua, et al.
Publicado: (2020)

Whole exome sequencing in Chinese mucinous pulmonary adenocarcinoma uncovers specific genetic variations different from lung adenocarcinoma
por: Zhang, Chenyue, et al.
Publicado: (2022)

Comprehensive Profiling of Gene Copy Number Alterations Predicts Patient Prognosis in Resected Stages I–III Lung Adenocarcinoma
por: Han, Xiaohong, et al.
Publicado: (2019)

Transcriptomic Alterations in Lung Adenocarcinoma Unveil New Mechanisms Targeted by the TBX2 Subfamily of Tumor Suppressor Genes
por: Khalil, Athar, et al.
Publicado: (2018)

Distinct gene mutation profiles among multiple and single primary lung adenocarcinoma
por: Wang, Yadong, et al.
Publicado: (2022)

Prognostic Impact of the Angiogenic Gene POSTN and Its Related Genes on Lung Adenocarcinoma
por: Sun, Dongfeng, et al.
Publicado: (2022)

Bronchial Washing Fluid Versus Plasma and Bronchoscopy Biopsy Samples for Detecting Epidermal Growth Factor Receptor Mutation Status in Lung Cancer
por: Zhang, Xinyu, et al.
Publicado: (2021)

A Potential Biomarker of Combination of Tumor Mutation Burden and Copy Number Alteration for Efficacy of Immunotherapy in KRAS-Mutant Advanced Lung Adenocarcinoma
por: Xiang, Luochengling, et al.
Publicado: (2020)

Profiling Oncogenic Germline Mutations in Unselected Chinese Lung Cancer Patients
por: Yang, Jie, et al.
Publicado: (2021)

Genomic Profiling Reveals Synchronous Bilateral Lung Adenocarcinomas With Distinct Driver Alterations of EML4-ALK or TPM3-ROS1 Fusion: A Case Report
por: Tan, Benxu, et al.
Publicado: (2019)

SPTBN2, a New Biomarker of Lung Adenocarcinoma
por: Wu, Chunli, et al.
Publicado: (2021)

Genomic And Tumor Microenvironment Differences Between Cell Cycle Progression Pathway Altered/Non-Altered Patients With Lung Adenocarcinoma
por: Shan, Guangyao, et al.
Publicado: (2022)

Comprehensive Analysis of the Function, Immune Profiles, and Clinical Implication of m1A Regulators in Lung Adenocarcinoma
por: Bao, Guangyao, et al.
Publicado: (2022)

Development of a Prognostic Alternative Splicing Signature Associated With Tumor Microenvironment Immune Profiles in Lung Adenocarcinoma
por: Bao, Guangyao, et al.
Publicado: (2022)

Effect of TTN Mutations on Immune Microenvironment and Efficacy of Immunotherapy in Lung Adenocarcinoma Patients
por: Wang, Zhe, et al.
Publicado: (2021)

Chemical and Biological Evidence of the Efficacy of Shengxian Decoction for Treating Human Lung Adenocarcinoma
por: Li, Kejuan, et al.
Publicado: (2022)

Efficacy and Resistance of Afatinib in Chinese Non-Small Cell Lung Cancer Patients With HER2 Alterations: A Multicenter Retrospective Study
por: Song, Zhengbo, et al.
Publicado: (2021)

Predictive Efficacy of a Radiomics Random Forest Model for Identifying Pathological Subtypes of Lung Adenocarcinoma Presenting as Ground-Glass Nodules
por: Zhao, Fen-hua, et al.
Publicado: (2022)

The Diagnostic Potential of SHOX2 and RASSF1A DNA Methylation in Early Lung Adenocarcinoma
por: Gao, Hong, et al.
Publicado: (2022)

Molecular Alterations in Lung Adenocarcinoma With Ground-Glass Nodules: A Systematic Review and Meta-Analysis
por: Wei, Zihan, et al.
Publicado: (2021)

Integrated Multiomics Analyses Revealing Different Molecular Profiles Between Early- and Late-Stage Lung Adenocarcinoma
por: Yue, Dongsheng, et al.
Publicado: (2021)

Targeting Genomic Alterations in Squamous Cell Lung Cancer
por: Mantripragada, Kalyan, et al.
Publicado: (2013)

Clinicopathological Characteristics and Mutation Spectrum of Colorectal Adenocarcinoma With Mucinous Component in a Chinese Cohort: Comparison With Classical Adenocarcinoma
por: Chen, Jingci, et al.
Publicado: (2020)

Cuproptosis-related signature predicts prognosis, immunotherapy efficacy, and chemotherapy sensitivity in lung adenocarcinoma
por: Wu, Gujie, et al.
Publicado: (2023)

Deciphering Prognostic Value of TTN and Its Correlation With Immune Infiltration in Lung Adenocarcinoma
por: Chen, Jianing, et al.
Publicado: (2022)

Germline Predisposition and Copy Number Alteration in Pre-stage Lung Adenocarcinomas Presenting as Ground-Glass Nodules
por: Ren, Yijiu, et al.
Publicado: (2019)

An Immune-Related lncRNA Expression Profile to Improve Prognosis Prediction for Lung Adenocarcinoma: From Bioinformatics to Clinical Word
por: Zhang, Boxiang, et al.
Publicado: (2021)

Papillary Adenocarcinoma: A Rare Subtype of Lung Adenocarcinoma
por: Thouil, Afaf, et al.
Publicado: (2023)

CT Texture Analysis for Differentiating Bronchiolar Adenoma, Adenocarcinoma In Situ, and Minimally Invasive Adenocarcinoma of the Lung
por: Sun, Jinju, et al.
Publicado: (2021)

Role of cuproptosis-related gene in lung adenocarcinoma
por: Liu, Yuan, et al.
Publicado: (2022)

Predictors of Lung Adenocarcinoma With Leptomeningeal Metastases: A 2022 Targeted-Therapy-Assisted molGPA Model
por: Zhang, Milan, et al.
Publicado: (2022)

The efficacy of neoadjuvant EGFR-TKI therapy combined with radical surgery for stage IIIB lung adenocarcinoma harboring EGFR mutations: A retrospective analysis based on single center
por: Xiong, Yicheng, et al.
Publicado: (2023)

Mutational Portrait of Lung Adenocarcinoma in Brazilian Patients: Past, Present, and Future of Molecular Profiling in the Clinic
por: Freitas, Helano C., et al.
Publicado: (2020)

Computed tomography-based radiomics quantification predicts epidermal growth factor receptor mutation status and efficacy of first-line targeted therapy in lung adenocarcinoma
por: Jiang, Meilin, et al.
Publicado: (2022)

Development of an Oncogenic Driver Alteration Associated Immune-Related Prognostic Model for Stage I-II Lung Adenocarcinoma
por: Xu, Jian-Zhao, et al.
Publicado: (2021)

A Classifier for Improving Early Lung Cancer Diagnosis Incorporating Artificial Intelligence and Liquid Biopsy
por: Ye, Maosong, et al.
Publicado: (2022)

KIF11 Serves as an Independent Prognostic Factor and Therapeutic Target for Patients With Lung Adenocarcinoma
por: Li, Zhaodong, et al.
Publicado: (2021)

A Seven Immune-Related lncRNAs Model to Increase the Predicted Value of Lung Adenocarcinoma
por: Li, Jian-Ping, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_29vfbft1v5h04lv4bpp2aicbp0