Adenosine-to-inosine RNA editing contributes to type I interferon responses in systemic sclerosis

OBJECTIVE: Adenosine deaminase acting on RNA-1 (ADAR1) enzyme is a type I interferon (IFN)-stimulated gene (ISG) catalyzing the deamination of adenosine-to-inosine, a process called A-to-I RNA editing. A-to-I RNA editing takes place mainly in Alu elements comprising a primate-specific level of post-...

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Detalles Bibliográficos
Autores principales: Vlachogiannis, Nikolaos I., Tual-Chalot, Simon, Zormpas, Eleftherios, Bonini, Francesca, Ntouros, Panagiotis A., Pappa, Maria, Bournia, Vasiliki-Kalliopi, Tektonidou, Maria G., Souliotis, Vassilis L., Mavragani, Clio P., Stamatelopoulos, Kimon, Gatsiou, Aikaterini, Sfikakis, Petros P., Stellos, Konstantinos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8713031/
https://www.ncbi.nlm.nih.gov/pubmed/34857436
http://dx.doi.org/10.1016/j.jaut.2021.102755

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