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Filamentous fungal applications in biotechnology: a combined bibliometric and patentometric assessment

BACKGROUND: Processes and products employing filamentous fungi are increasing contributors to biotechnology. These organisms are used as cell factories for the synthesis of platform chemicals, enzymes, acids, foodstuffs and therapeutics. More recent applications include processing biomass into const...

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Detalles Bibliográficos
Autores principales: Füting, Pamina, Barthel, Lars, Cairns, Timothy C., Briesen, Heiko, Schmideder, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8713403/
https://www.ncbi.nlm.nih.gov/pubmed/34963476
http://dx.doi.org/10.1186/s40694-021-00131-6
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author Füting, Pamina
Barthel, Lars
Cairns, Timothy C.
Briesen, Heiko
Schmideder, Stefan
author_facet Füting, Pamina
Barthel, Lars
Cairns, Timothy C.
Briesen, Heiko
Schmideder, Stefan
author_sort Füting, Pamina
collection PubMed
description BACKGROUND: Processes and products employing filamentous fungi are increasing contributors to biotechnology. These organisms are used as cell factories for the synthesis of platform chemicals, enzymes, acids, foodstuffs and therapeutics. More recent applications include processing biomass into construction or textile materials. These exciting advances raise several interrelated questions regarding the contributions of filamentous fungi to biotechnology. For example, are advances in this discipline a major contributor compared to other organisms, e.g. plants or bacteria? From a geographical perspective, where is this work conducted? Which species are predominantly used? How do biotech companies actually use these organisms? RESULTS: To glean a snapshot of the state of the discipline, literature (bibliometry) and patent (patentometry) outputs of filamentous fungal applications and the related fields were quantitatively surveyed. How these outputs vary across fungal species, industrial application(s), geographical locations and biotechnological companies were analysed. Results identified (i) fungi as crucial drivers for publications and patents in biotechnology, (ii) enzyme and organic acid production as the main applications, (iii) Aspergillus as the most commonly used genus by biotechnologists, (iv) China, the United States, Brazil, and Europe as the leaders in filamentous fungal science, and (v) the key players in industrial biotechnology. CONCLUSIONS: This study generated a summary of the status of filamentous fungal applications in biotechnology. Both bibliometric and patentometric data have identified several key trends, breakthroughs and challenges faced by the fungal research community. The analysis suggests that the future is bright for filamentous fungal research worldwide. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s40694-021-00131-6.
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spelling pubmed-87134032022-01-05 Filamentous fungal applications in biotechnology: a combined bibliometric and patentometric assessment Füting, Pamina Barthel, Lars Cairns, Timothy C. Briesen, Heiko Schmideder, Stefan Fungal Biol Biotechnol Research BACKGROUND: Processes and products employing filamentous fungi are increasing contributors to biotechnology. These organisms are used as cell factories for the synthesis of platform chemicals, enzymes, acids, foodstuffs and therapeutics. More recent applications include processing biomass into construction or textile materials. These exciting advances raise several interrelated questions regarding the contributions of filamentous fungi to biotechnology. For example, are advances in this discipline a major contributor compared to other organisms, e.g. plants or bacteria? From a geographical perspective, where is this work conducted? Which species are predominantly used? How do biotech companies actually use these organisms? RESULTS: To glean a snapshot of the state of the discipline, literature (bibliometry) and patent (patentometry) outputs of filamentous fungal applications and the related fields were quantitatively surveyed. How these outputs vary across fungal species, industrial application(s), geographical locations and biotechnological companies were analysed. Results identified (i) fungi as crucial drivers for publications and patents in biotechnology, (ii) enzyme and organic acid production as the main applications, (iii) Aspergillus as the most commonly used genus by biotechnologists, (iv) China, the United States, Brazil, and Europe as the leaders in filamentous fungal science, and (v) the key players in industrial biotechnology. CONCLUSIONS: This study generated a summary of the status of filamentous fungal applications in biotechnology. Both bibliometric and patentometric data have identified several key trends, breakthroughs and challenges faced by the fungal research community. The analysis suggests that the future is bright for filamentous fungal research worldwide. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s40694-021-00131-6. BioMed Central 2021-12-28 /pmc/articles/PMC8713403/ /pubmed/34963476 http://dx.doi.org/10.1186/s40694-021-00131-6 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Füting, Pamina
Barthel, Lars
Cairns, Timothy C.
Briesen, Heiko
Schmideder, Stefan
Filamentous fungal applications in biotechnology: a combined bibliometric and patentometric assessment
title Filamentous fungal applications in biotechnology: a combined bibliometric and patentometric assessment
title_full Filamentous fungal applications in biotechnology: a combined bibliometric and patentometric assessment
title_fullStr Filamentous fungal applications in biotechnology: a combined bibliometric and patentometric assessment
title_full_unstemmed Filamentous fungal applications in biotechnology: a combined bibliometric and patentometric assessment
title_short Filamentous fungal applications in biotechnology: a combined bibliometric and patentometric assessment
title_sort filamentous fungal applications in biotechnology: a combined bibliometric and patentometric assessment
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8713403/
https://www.ncbi.nlm.nih.gov/pubmed/34963476
http://dx.doi.org/10.1186/s40694-021-00131-6
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