Lattice defects induced by microtubule-stabilizing agents exert a long-range effect on microtubule growth by promoting catastrophes

Microtubules are dynamic cytoskeletal polymers that spontaneously switch between phases of growth and shrinkage. The probability of transitioning from growth to shrinkage, termed catastrophe, increases with microtubule age, but the underlying mechanisms are poorly understood. Here, we set out to tes...

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Detalles Bibliográficos
Autores principales: Rai, Ankit, Liu, Tianyang, Katrukha, Eugene A., Estévez-Gallego, Juan, Manka, Szymon W., Paterson, Ian, Díaz, J. Fernando, Kapitein, Lukas C., Moores, Carolyn A., Akhmanova, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8713758/
https://www.ncbi.nlm.nih.gov/pubmed/34916292
http://dx.doi.org/10.1073/pnas.2112261118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8713758/
https://www.ncbi.nlm.nih.gov/pubmed/34916292
http://dx.doi.org/10.1073/pnas.2112261118

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