The cyclic dinucleotide 2′3′-cGAMP induces a broad antibacterial and antiviral response in the sea anemone Nematostella vectensis

In mammals, cyclic dinucleotides (CDNs) bind and activate STING to initiate an antiviral type I interferon response. CDNs and STING originated in bacteria and are present in most animals. By contrast, interferons are believed to have emerged in vertebrates; thus, the function of CDN signaling in inv...

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Detalles Bibliográficos
Autores principales: Margolis, Shally R., Dietzen, Peter A., Hayes, Beth M., Wilson, Stephen C., Remick, Brenna C., Chou, Seemay, Vance, Russell E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8713801/
https://www.ncbi.nlm.nih.gov/pubmed/34903650
http://dx.doi.org/10.1073/pnas.2109022118

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