N6-methyladenosine (m(6)A) depletion regulates pluripotency exit by activating signaling pathways in embryonic stem cells

N6-methyladenosine (m(6)A) deposition on messenger RNA (mRNA) controls embryonic stem cell (ESC) fate by regulating the mRNA stabilities of pluripotency and lineage transcription factors (TFs) [P. J. Batista et al., Cell Stem Cell 15, 707–719 (2014); Y. Wang et al., Nat. Cell Biol. 16, 191–198 (2014...

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Detalles Bibliográficos
Autores principales: Jin, Kang-Xuan, Zuo, Rujuan, Anastassiadis, Konstantinos, Klungland, Arne, Marr, Carsten, Filipczyk, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8713808/
https://www.ncbi.nlm.nih.gov/pubmed/34921114
http://dx.doi.org/10.1073/pnas.2105192118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8713808/
https://www.ncbi.nlm.nih.gov/pubmed/34921114
http://dx.doi.org/10.1073/pnas.2105192118

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