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Discovery of an ancient MHC category with both class I and class II features

Two classes of major histocompatibility complex (MHC) molecules, MHC class I and class II, play important roles in our immune system, presenting antigens to functionally distinct T lymphocyte populations. However, the origin of this essential MHC class divergence is poorly understood. Here, we disco...

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Detalles Bibliográficos
Autores principales:	Okamura, Kazuhiko, Dijkstra, Johannes M., Tsukamoto, Kentaro, Grimholt, Unni, Wiegertjes, Geert F., Kondow, Akiko, Yamaguchi, Hisateru, Hashimoto, Keiichiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2021
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8713811/ https://www.ncbi.nlm.nih.gov/pubmed/34903649 http://dx.doi.org/10.1073/pnas.2108104118

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