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Low-energy electron holography imaging of conformational variability of single-antibody molecules from electrospray ion beam deposition
Imaging of proteins at the single-molecule level can reveal conformational variability, which is essential for the understanding of biomolecules. To this end, a biologically relevant state of the sample must be retained during both sample preparation and imaging. Native electrospray ionization (ESI)...
Autores principales: | Ochner, Hannah, Szilagyi, Sven, Abb, Sabine, Gault, Joseph, Robinson, Carol V., Malavolti, Luigi, Rauschenbach, Stephan, Kern, Klaus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8713884/ https://www.ncbi.nlm.nih.gov/pubmed/34911762 http://dx.doi.org/10.1073/pnas.2112651118 |
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