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IGFBP-6/sonic hedgehog/TLR4 signalling axis drives bone marrow fibrotic transformation in primary myelofibrosis

Primary myelofibrosis is a Ph-negative chronic myeloproliferative neoplasm characterized by bone marrow fibrosis and associated with the involvement of several pathways, in addition to bone marrow microenvironment alterations, mostly driven by the activation of the cytokine receptor/JAK2 pathway. Id...

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Detalles Bibliográficos
Autores principales:	Longhitano, Lucia, Tibullo, Daniele, Vicario, Nunzio, Giallongo, Cesarina, La Spina, Enrico, Romano, Alessandra, Lombardo, Sofia, Moretti, Marina, Masia, Francesco, Coda, Anna Rita Daniela, Venuto, Santina, Fontana, Paolo, Parenti, Rosalba, Li Volti, Giovanni, Di Rosa, Michelino, Palumbo, Giuseppe A., Liso, Arcangelo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8714138/ https://www.ncbi.nlm.nih.gov/pubmed/34905501 http://dx.doi.org/10.18632/aging.203779

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