hsa_circ_0072389, hsa_circ_0072386, hsa_circ_0008621, hsa_circ_0072387, and hsa_circ_0072391 aggravate glioma via miR-338-5p/IKBIP

Glioma is a primary intracranial tumor with high morbidity and mortality. We acquired miR-338-5p, which suppresses the development of glioma, from the GEO and CGGA databases. In addition, we predicted that hsa_circ_0072389, hsa_circ_0072386, hsa_circ_0008621, hsa_circ_0072387, and hsa_circ_0072391 c...

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Detalles Bibliográficos
Autores principales: Liang, Jian, Li, Xing, Xu, Jian, Cai, Guang-Mou, Cao, Jian-Xuan, Zhang, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8714164/
https://www.ncbi.nlm.nih.gov/pubmed/34897031
http://dx.doi.org/10.18632/aging.203740
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author Liang, Jian
Li, Xing
Xu, Jian
Cai, Guang-Mou
Cao, Jian-Xuan
Zhang, Bo
author_facet Liang, Jian
Li, Xing
Xu, Jian
Cai, Guang-Mou
Cao, Jian-Xuan
Zhang, Bo
author_sort Liang, Jian
collection PubMed
description Glioma is a primary intracranial tumor with high morbidity and mortality. We acquired miR-338-5p, which suppresses the development of glioma, from the GEO and CGGA databases. In addition, we predicted that hsa_circ_0072389, hsa_circ_0072386, hsa_circ_0008621, hsa_circ_0072387, and hsa_circ_0072391 could relieve the silencing of IKBIP by miR-338-5p. By analyzing genes related to IKBIP expression, possible pathways affecting glioma were identified. This study provides new ideas for investigating multiple circRNAs in ceRNAs.
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spelling pubmed-87141642021-12-29 hsa_circ_0072389, hsa_circ_0072386, hsa_circ_0008621, hsa_circ_0072387, and hsa_circ_0072391 aggravate glioma via miR-338-5p/IKBIP Liang, Jian Li, Xing Xu, Jian Cai, Guang-Mou Cao, Jian-Xuan Zhang, Bo Aging (Albany NY) Research Paper Glioma is a primary intracranial tumor with high morbidity and mortality. We acquired miR-338-5p, which suppresses the development of glioma, from the GEO and CGGA databases. In addition, we predicted that hsa_circ_0072389, hsa_circ_0072386, hsa_circ_0008621, hsa_circ_0072387, and hsa_circ_0072391 could relieve the silencing of IKBIP by miR-338-5p. By analyzing genes related to IKBIP expression, possible pathways affecting glioma were identified. This study provides new ideas for investigating multiple circRNAs in ceRNAs. Impact Journals 2021-12-12 /pmc/articles/PMC8714164/ /pubmed/34897031 http://dx.doi.org/10.18632/aging.203740 Text en Copyright: © 2021 Liang et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/3.0/) (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Paper
Liang, Jian
Li, Xing
Xu, Jian
Cai, Guang-Mou
Cao, Jian-Xuan
Zhang, Bo
hsa_circ_0072389, hsa_circ_0072386, hsa_circ_0008621, hsa_circ_0072387, and hsa_circ_0072391 aggravate glioma via miR-338-5p/IKBIP
title hsa_circ_0072389, hsa_circ_0072386, hsa_circ_0008621, hsa_circ_0072387, and hsa_circ_0072391 aggravate glioma via miR-338-5p/IKBIP
title_full hsa_circ_0072389, hsa_circ_0072386, hsa_circ_0008621, hsa_circ_0072387, and hsa_circ_0072391 aggravate glioma via miR-338-5p/IKBIP
title_fullStr hsa_circ_0072389, hsa_circ_0072386, hsa_circ_0008621, hsa_circ_0072387, and hsa_circ_0072391 aggravate glioma via miR-338-5p/IKBIP
title_full_unstemmed hsa_circ_0072389, hsa_circ_0072386, hsa_circ_0008621, hsa_circ_0072387, and hsa_circ_0072391 aggravate glioma via miR-338-5p/IKBIP
title_short hsa_circ_0072389, hsa_circ_0072386, hsa_circ_0008621, hsa_circ_0072387, and hsa_circ_0072391 aggravate glioma via miR-338-5p/IKBIP
title_sort hsa_circ_0072389, hsa_circ_0072386, hsa_circ_0008621, hsa_circ_0072387, and hsa_circ_0072391 aggravate glioma via mir-338-5p/ikbip
topic Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8714164/
https://www.ncbi.nlm.nih.gov/pubmed/34897031
http://dx.doi.org/10.18632/aging.203740
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