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Repurposing of FDA-approved drugs as potential inhibitors of the SARS-CoV-2 main protease: Molecular insights into improved therapeutic discovery

With numerous infections and fatalities, COVID-19 has wreaked havoc around the globe. The main protease (Mpro), which cleaves the polyprotein to form non-structural proteins, thereby helping in the replication of SARS-CoV-2, appears as an attractive target for antiviral therapeutics. As FDA-approved...

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Detalles Bibliográficos
Autores principales:	Ray, Abhik Kumar, Sen Gupta, Parth Sarthi, Panda, Saroj Kumar, Biswal, Satyaranjan, Bhattacharya, Uddipan, Rana, Malay Kumar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Ltd. 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8714248/ https://www.ncbi.nlm.nih.gov/pubmed/34986429 http://dx.doi.org/10.1016/j.compbiomed.2021.105183

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