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Analysis of a nonstandard computer method to simulate a nonlinear stochastic epidemiological model of coronavirus-like diseases

Background and objective: We propose a nonstandard computational model to approximate the solutions of a stochastic system describing the propagation of an infectious disease. The mathematical model considers the existence of various sub-populations, including humans who are susceptible to the disea...

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Autores principales: Macías-Díaz, J.E., Raza, Ali, Ahmed, Nauman, Rafiq, Muhammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8714259/
https://www.ncbi.nlm.nih.gov/pubmed/33813059
http://dx.doi.org/10.1016/j.cmpb.2021.106054
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author Macías-Díaz, J.E.
Raza, Ali
Ahmed, Nauman
Rafiq, Muhammad
author_facet Macías-Díaz, J.E.
Raza, Ali
Ahmed, Nauman
Rafiq, Muhammad
author_sort Macías-Díaz, J.E.
collection PubMed
description Background and objective: We propose a nonstandard computational model to approximate the solutions of a stochastic system describing the propagation of an infectious disease. The mathematical model considers the existence of various sub-populations, including humans who are susceptible to the disease, asymptomatic humans, infected humans and recovered or quarantined individuals. Various mechanisms of propagation are considered in order to describe the propagation phenomenon accurately. Methods: We propose a stochastic extension of the deterministic model, considering a random component which follows a Brownian motion. In view of the difficulties to solve the system exactly, we propose a computational model to approximate its solutions following a nonstandard approach. Results: The nonstandard discretization is fully analyzed for positivity, boundedness and stability. It is worth pointing out that these properties are realized in the discrete scenario and that they are thoroughly established herein using rigorous mathematical arguments. We provide some illustrative computational simulations to exhibit the main computational features of this approach. Conclusions: The results show that the nonstandard technique is capable of preserving the distinctive characteristics of the epidemiologically relevant solutions of the model, while other (classical) approaches are not able to do it. For the sake of convenience, a computational code of the nonstandard discrete model may be provided to the readers at their requests.
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spelling pubmed-87142592021-12-29 Analysis of a nonstandard computer method to simulate a nonlinear stochastic epidemiological model of coronavirus-like diseases Macías-Díaz, J.E. Raza, Ali Ahmed, Nauman Rafiq, Muhammad Comput Methods Programs Biomed Article Background and objective: We propose a nonstandard computational model to approximate the solutions of a stochastic system describing the propagation of an infectious disease. The mathematical model considers the existence of various sub-populations, including humans who are susceptible to the disease, asymptomatic humans, infected humans and recovered or quarantined individuals. Various mechanisms of propagation are considered in order to describe the propagation phenomenon accurately. Methods: We propose a stochastic extension of the deterministic model, considering a random component which follows a Brownian motion. In view of the difficulties to solve the system exactly, we propose a computational model to approximate its solutions following a nonstandard approach. Results: The nonstandard discretization is fully analyzed for positivity, boundedness and stability. It is worth pointing out that these properties are realized in the discrete scenario and that they are thoroughly established herein using rigorous mathematical arguments. We provide some illustrative computational simulations to exhibit the main computational features of this approach. Conclusions: The results show that the nonstandard technique is capable of preserving the distinctive characteristics of the epidemiologically relevant solutions of the model, while other (classical) approaches are not able to do it. For the sake of convenience, a computational code of the nonstandard discrete model may be provided to the readers at their requests. Elsevier B.V. 2021-06 2021-03-20 /pmc/articles/PMC8714259/ /pubmed/33813059 http://dx.doi.org/10.1016/j.cmpb.2021.106054 Text en © 2021 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Macías-Díaz, J.E.
Raza, Ali
Ahmed, Nauman
Rafiq, Muhammad
Analysis of a nonstandard computer method to simulate a nonlinear stochastic epidemiological model of coronavirus-like diseases
title Analysis of a nonstandard computer method to simulate a nonlinear stochastic epidemiological model of coronavirus-like diseases
title_full Analysis of a nonstandard computer method to simulate a nonlinear stochastic epidemiological model of coronavirus-like diseases
title_fullStr Analysis of a nonstandard computer method to simulate a nonlinear stochastic epidemiological model of coronavirus-like diseases
title_full_unstemmed Analysis of a nonstandard computer method to simulate a nonlinear stochastic epidemiological model of coronavirus-like diseases
title_short Analysis of a nonstandard computer method to simulate a nonlinear stochastic epidemiological model of coronavirus-like diseases
title_sort analysis of a nonstandard computer method to simulate a nonlinear stochastic epidemiological model of coronavirus-like diseases
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8714259/
https://www.ncbi.nlm.nih.gov/pubmed/33813059
http://dx.doi.org/10.1016/j.cmpb.2021.106054
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