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Comparison of bone mineral density and vertebral fracture assessment in postmenopausal women with and without distal radius fractures
OBJECTIVES: To compare bone mineral density (BMD) in Thai postmenopausal women with and without distal radius fracture, and to investigate the role of vertebral fracture assessment (VFA) in diagnosing osteoporosis after distal radius fracture. METHODS: A cross-sectional study was conducted in Thai p...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society of Osteoporosis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8714471/ https://www.ncbi.nlm.nih.gov/pubmed/35005249 http://dx.doi.org/10.1016/j.afos.2021.11.004 |
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author | Amphansap, Tanawat Rattanaphonglekha, Chayaphong Vechasilp, Jaruwat Stitkitti, Nitirat Apiromyanont, Kamonchalat Therdyothin, Atiporn |
author_facet | Amphansap, Tanawat Rattanaphonglekha, Chayaphong Vechasilp, Jaruwat Stitkitti, Nitirat Apiromyanont, Kamonchalat Therdyothin, Atiporn |
author_sort | Amphansap, Tanawat |
collection | PubMed |
description | OBJECTIVES: To compare bone mineral density (BMD) in Thai postmenopausal women with and without distal radius fracture, and to investigate the role of vertebral fracture assessment (VFA) in diagnosing osteoporosis after distal radius fracture. METHODS: A cross-sectional study was conducted in Thai postmenopausal women with and without distal radius fracture. BMDs of the femoral neck (FN), total hip (TH), lumbar spine (LS), and VFA were obtained within 2 weeks of injury. BMD were compared between groups. Participants were classified into osteoporosis, osteopenia or normal using BMD alone, and BMD plus VFA, where a mere presence of vertebral compression fracture indicated osteoporosis. RESULTS: Fifty postmenopausal women with distal radius fractures and 111 non-fracture postmenopausal women participated. The mean BMD was significantly lower at all sites in the fracture group (FN BMD 0.590 ± 0.075 vs 0.671 ± 0.090, p = 0.007; TH BMD 0.742 ± 0.103 vs 0.828 ± 0.116, P = 0.009; LS BMD 0.799 ± 0.107 vs 0.890 ± 0.111, P = 0.009 in the fracture vs non-fracture group respectively). VFA increased the prevalence of osteoporosis from 16 (32%) to 23 (46%) in the fracture group, and 7 (6.31%) to 17 (16.22%) in the non-fracture group, with a number needed to treat 9. CONCLUSIONS: Postmenopausal women with distal radius fractures had lower BMD. Incorporating VFA into diagnosis of osteoporosis increased the prevalence of osteoporosis in both fracture and non-fracture groups. Postmenopausal women aged 50 years or older with distal radius fracture are a good target for the investigation of osteoporosis. |
format | Online Article Text |
id | pubmed-8714471 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Korean Society of Osteoporosis |
record_format | MEDLINE/PubMed |
spelling | pubmed-87144712022-01-06 Comparison of bone mineral density and vertebral fracture assessment in postmenopausal women with and without distal radius fractures Amphansap, Tanawat Rattanaphonglekha, Chayaphong Vechasilp, Jaruwat Stitkitti, Nitirat Apiromyanont, Kamonchalat Therdyothin, Atiporn Osteoporos Sarcopenia Original Article OBJECTIVES: To compare bone mineral density (BMD) in Thai postmenopausal women with and without distal radius fracture, and to investigate the role of vertebral fracture assessment (VFA) in diagnosing osteoporosis after distal radius fracture. METHODS: A cross-sectional study was conducted in Thai postmenopausal women with and without distal radius fracture. BMDs of the femoral neck (FN), total hip (TH), lumbar spine (LS), and VFA were obtained within 2 weeks of injury. BMD were compared between groups. Participants were classified into osteoporosis, osteopenia or normal using BMD alone, and BMD plus VFA, where a mere presence of vertebral compression fracture indicated osteoporosis. RESULTS: Fifty postmenopausal women with distal radius fractures and 111 non-fracture postmenopausal women participated. The mean BMD was significantly lower at all sites in the fracture group (FN BMD 0.590 ± 0.075 vs 0.671 ± 0.090, p = 0.007; TH BMD 0.742 ± 0.103 vs 0.828 ± 0.116, P = 0.009; LS BMD 0.799 ± 0.107 vs 0.890 ± 0.111, P = 0.009 in the fracture vs non-fracture group respectively). VFA increased the prevalence of osteoporosis from 16 (32%) to 23 (46%) in the fracture group, and 7 (6.31%) to 17 (16.22%) in the non-fracture group, with a number needed to treat 9. CONCLUSIONS: Postmenopausal women with distal radius fractures had lower BMD. Incorporating VFA into diagnosis of osteoporosis increased the prevalence of osteoporosis in both fracture and non-fracture groups. Postmenopausal women aged 50 years or older with distal radius fracture are a good target for the investigation of osteoporosis. Korean Society of Osteoporosis 2021-12 2021-12-04 /pmc/articles/PMC8714471/ /pubmed/35005249 http://dx.doi.org/10.1016/j.afos.2021.11.004 Text en © 2021 The Korean Society of Osteoporosis. Publishing services by Elsevier B.V. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Original Article Amphansap, Tanawat Rattanaphonglekha, Chayaphong Vechasilp, Jaruwat Stitkitti, Nitirat Apiromyanont, Kamonchalat Therdyothin, Atiporn Comparison of bone mineral density and vertebral fracture assessment in postmenopausal women with and without distal radius fractures |
title | Comparison of bone mineral density and vertebral fracture assessment in postmenopausal women with and without distal radius fractures |
title_full | Comparison of bone mineral density and vertebral fracture assessment in postmenopausal women with and without distal radius fractures |
title_fullStr | Comparison of bone mineral density and vertebral fracture assessment in postmenopausal women with and without distal radius fractures |
title_full_unstemmed | Comparison of bone mineral density and vertebral fracture assessment in postmenopausal women with and without distal radius fractures |
title_short | Comparison of bone mineral density and vertebral fracture assessment in postmenopausal women with and without distal radius fractures |
title_sort | comparison of bone mineral density and vertebral fracture assessment in postmenopausal women with and without distal radius fractures |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8714471/ https://www.ncbi.nlm.nih.gov/pubmed/35005249 http://dx.doi.org/10.1016/j.afos.2021.11.004 |
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