Strategies to Circumvent the Side-Effects of Immunotherapy Using Allogeneic CAR-T Cells and Boost Its Efficacy: Results of Recent Clinical Trials

Despite the outstanding results of treatment using autologous chimeric antigen receptor T cells (CAR-T cells) in hematological malignancies, this approach is endowed with several constraints. In particular, profound lymphopenia in some patients and the inability to manufacture products with predefin...

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Detalles Bibliográficos
Autores principales: Smirnov, Sergei, Petukhov, Alexey, Levchuk, Ksenia, Kulemzin, Sergey, Staliarova, Alena, Lepik, Kirill, Shuvalov, Oleg, Zaritskey, Andrey, Daks, Alexandra, Fedorova, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8714645/
https://www.ncbi.nlm.nih.gov/pubmed/34975869
http://dx.doi.org/10.3389/fimmu.2021.780145

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