Recovery of Latent HIV-1 from Brain Tissue by Adoptive Cell Transfer in Virally Suppressed Humanized Mice

Defining the latent human immunodeficiency virus type 1 (HIV-1) burden in the human brain during progressive infection is limited by sample access. Human hematopoietic stem cells (hu-HSCs)-reconstituted humanized mice provide an opportunity for this study. The model mimics, in measure, HIV-1 pathoph...

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Detalles Bibliográficos
Autores principales: Su, Hang, Sravanam, Sruthi, Sillman, Brady, Waight, Emiko, Makarov, Edward, Mathews, Saumi, Poluektova, Larisa Y., Gorantla, Santhi, Gendelman, Howard E., Dash, Prasanta K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8714687/
https://www.ncbi.nlm.nih.gov/pubmed/34528173
http://dx.doi.org/10.1007/s11481-021-10011-w

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