Cargando…

Randomized evaluation of quizartinib and low-dose ara-C vs low-dose ara-C in older acute myeloid leukemia patients

Survival for older patients with acute myeloid leukemia (AML) unsuitable for intensive chemotherapy is unsatisfactory. Standard nonintensive therapies have low response rates and only extend life by a few months. Quizartinib is an oral Fms-like tyrosine kinase 3 (FLT3) inhibitor with reported activi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dennis, Mike, Thomas, Ian F., Ariti, Cono, Upton, Laura, Burnett, Alan K., Gilkes, Amanda, Radia, Rohini, Hemmaway, Claire, Mehta, Priyanka, Knapper, Steven, Clark, Richard E., Copland, Mhairi, Russell, Nigel, Hills, Robert K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Hematology 2021
Materias:	Stimulus Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8714727/ https://www.ncbi.nlm.nih.gov/pubmed/34597366 http://dx.doi.org/10.1182/bloodadvances.2021005038

Ejemplares similares

The Addition of Arsenic Trioxide to Low Dose Ara-C in Older Patients with AML Does Not Improve Outcome
por: Burnett, Alan K, et al.
Publicado: (2011)

High-dose cytosine arabinoside (Ara-C) in colorectal cancer.
por: Kanojia, M., et al.
Publicado: (1983)

Low dose docosahexaenoic acid protects normal colonic epithelial cells from araC toxicity
por: Cha, Ming C, et al.
Publicado: (2005)

Q-HAM: a multicenter upfront randomized phase II trial of quizartinib and high-dose Ara-C plus mitoxantrone in relapsed/refractory AML with FLT3-ITD
por: Jaramillo, Sonia, et al.
Publicado: (2023)

DNA tape measurements of AraC
por: Rodgers, Michael E., et al.
Publicado: (2008)

Liposomally trapped AraCTP to overcome AraC resistance in a murine lymphoma in vitro.
por: Richardson, V. J., et al.
Publicado: (1982)

An Improved Enzyme-Linked Immunosorbent Assay (ELISA) Based Protocol Using Seeds for Detection of Five Major Peanut Allergens Ara h 1, Ara h 2, Ara h 3, Ara h 6, and Ara h 8
por: Pandey, Arun K., et al.
Publicado: (2019)

Ara solar
por: Anguiano Valadez, Adolfo, 1917-
Publicado: (1974)

The Takata-Ara Test
por: Chaudhuri, R. N., et al.
Publicado: (1943)

The pharmacologic basis for the efficacy of high-dose Ara-C and sequential asparaginase in adult acute myelogenous leukemia.
por: Capizzi, R. L., et al.
Publicado: (1988)

IgE cross-reactivity between the major peanut allergen Ara h 2 and the non-homologous allergens Ara h 1 and Ara h 3
por: Bublin, M, et al.
Publicado: (2013)

Ara h 2 is the dominant peanut allergen despite similarities with Ara h 6
por: Hemmings, Oliver, et al.
Publicado: (2020)

Clinical impact of NPM1-mutant molecular persistence after chemotherapy for acute myeloid leukemia
por: Tiong, Ing S., et al.
Publicado: (2021)

El ara : instructivo para el aprendiz masón.
Publicado: (1974)

A comparison of clofarabine with ara-C, each in combination with daunorubicin as induction treatment in older patients with acute myeloid leukaemia
por: Burnett, A K, et al.
Publicado: (2017)

Eine neue Ära beginnt!
por: Klimek, Ludger, et al.
Publicado: (2020)

Optimization of cytarabine (ARA-C) therapy for acute myeloid leukemia
por: Momparler, Richard L
Publicado: (2013)

AraC-Based Biosensor for the Detection of Isoprene in E. coli
por: Bhat, Shrilaxmi, et al.
Publicado: (2023)

Ara h 6 complements Ara h 2 as an important marker for IgE reactivity to peanut
por: Hindley, J, et al.
Publicado: (2013)

Stabilization of SAMHD1 by NONO is crucial for Ara-C resistance in AML
por: Zhang, Feifei, et al.
Publicado: (2022)

Prognostic value of low-level MRD in adult acute lymphoblastic leukemia detected by low- and high-throughput methods
por: Kotrová, Michaela, et al.
Publicado: (2022)

Digestion and Transport across the Intestinal Epithelium Affects the Allergenicity of Ara h 1 and 3 but Not of Ara h 2 and 6
por: Smits, Mark, et al.
Publicado: (2021)

Circumvention of ara-C resistance by aphidicolin in blast cells from patients with AML
por: Sargent, J M, et al.
Publicado: (2001)

Characterisation of a putative AraC transcriptional regulator from Mycobacterium smegmatis
por: Evangelopoulos, Dimitrios, et al.
Publicado: (2014)

P1362: FEASIBILITY OF HAEMATOPOIETIC STEM CELL MOBILIZATION AFTER CONSOLIDATION WITH GEMTUZUMAB OZOGAMICIN AND INTERMEDIATE-DOSES ARA-C AND DAUNORUBICIN IN AML
por: Perrone, S., et al.
Publicado: (2022)

A new class of inhibitors of the AraC family virulence regulator Vibrio cholerae ToxT
por: Woodbrey, Anne K., et al.
Publicado: (2017)

Enhanced VWF clearance in low VWF pathogenesis: limitations of the VWFpp/VWF:Ag ratio and clinical significance
por: Doherty, Dearbhla, et al.
Publicado: (2022)

Radotinib enhances cytarabine (Ara-C)-induced acute myeloid leukemia cell death
por: Heo, Sook-Kyoung, et al.
Publicado: (2020)

Dexamethasone Sensitizes Acute Monocytic Leukemia Cells to Ara-C by Upregulating FKBP51
por: Sun, Huanxin, et al.
Publicado: (2022)

FoxR is an AraC‐like transcriptional regulator of ferrioxamine uptake in Salmonella enterica
por: Saldaña‐Ahuactzi, Zeus, et al.
Publicado: (2022)

Electrochemical Immunosensor for the Simultaneous Determination of Two Main Peanut Allergenic Proteins (Ara h 1 and Ara h 6) in Food Matrices
por: Freitas, Maria, et al.
Publicado: (2021)

Importance of Ara h 6 in peanut allergy diagnosis
por: Pedrosa, Maria, et al.
Publicado: (2014)

Evaluation of basophil allergen threshold sensitivity (CD-sens) to peanut and Ara h 8 in children IgE-sensitized to Ara h 8
por: Glaumann, Susanne, et al.
Publicado: (2015)

AraPheno and the AraGWAS Catalog 2020: a major database update including RNA-Seq and knockout mutation data for Arabidopsis thaliana
por: Togninalli, Matteo, et al.
Publicado: (2020)

Peanut lipids influence the response of bronchial epithelial cells to the peanut allergens Ara h 1 and Ara h 2 by decreasing barrier permeability
por: Palladino, Chiara, et al.
Publicado: (2023)

IgE cross-inhibition between Ara h 1 and Ara h 2 is explained by complex formation of both major peanut allergens
por: Warmenhoven, Hans J. M., et al.
Publicado: (2023)

Development and evaluation of mouse anti-Ara h 1 and Ara h 3 IgE monoclonal antibodies for advancing peanut allergy research
por: Waritani, Takaki, et al.
Publicado: (2023)

1-beta-D-arabinofuranosylcytosine (Ara-C) enhances mitochondrial activities in human leukaemic cells.
por: Muus, P., et al.
Publicado: (1991)

A large family of anti‐activators accompanying XylS/AraC family regulatory proteins
por: Santiago, Araceli E., et al.
Publicado: (2016)

The AraC Negative Regulator family modulates the activity of histone-like proteins in pathogenic bacteria
por: Santiago, Araceli E., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_hfog396l4q70rr7q3nh0vdgemo