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Rewards of divergence in sequences, 3-D structures and dynamics of yeast and human spliceosome SF3b complexes

The evolution of homologous and functionally equivalent multiprotein assemblies is intriguing considering sequence divergence of constituent proteins. Here, we studied the implications of protein sequence divergence on the structure, dynamics and function of homologous yeast and human SF3b spliceoso...

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Detalles Bibliográficos
Autores principales: Yazhini, Arangasamy, Sandhya, Sankaran, Srinivasan, Narayanaswamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8714771/
https://www.ncbi.nlm.nih.gov/pubmed/35028595
http://dx.doi.org/10.1016/j.crstbi.2021.05.003