α-Fetoprotein-Producing Endometrial Carcinoma Is Associated With Fetal Gut-Like and/or Hepatoid Morphology, Lymphovascular Infiltration, TP53 Abnormalities, and Poor Prognosis: Five Cases and Literature Review

The clinicopathological, immunohistochemical, and molecular characteristics of α-fetoprotein (AFP)-producing endometrial carcinoma (AFP+ EC) are poorly understood. From 284 cases of endometrial carcinoma in our pathology archive, we identified five cases (1.8%) of AFP+ EC with fetal gut–like (4/5) a...

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Detalles Bibliográficos
Autores principales: Otani, Tomoyuki, Murakami, Kosuke, Shiraishi, Naoki, Hagiyama, Man, Satou, Takao, Matsuki, Mitsuru, Matsumura, Noriomi, Ito, Akihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8714782/
https://www.ncbi.nlm.nih.gov/pubmed/34977100
http://dx.doi.org/10.3389/fmed.2021.799163

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