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Engineering immunoproteasome-expressing mesenchymal stromal cells: A potent cellular vaccine for lymphoma and melanoma in mice

Dendritic cells (DCs) excel at cross-presenting antigens, but their effectiveness as cancer vaccine is limited. Here, we describe a vaccination approach using mesenchymal stromal cells (MSCs) engineered to express the immunoproteasome complex (MSC-IPr). Such modification instills efficient antigen c...

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Detalles Bibliográficos
Autores principales:	Abusarah, Jamilah, Khodayarian, Fatemeh, El-Hachem, Nehme, Salame, Natasha, Olivier, Martin, Balood, Mohammad, Roversi, Katiane, Talbot, Sebastien, Bikorimana, Jean-Pierre, Chen, Jingkui, Jolicoeur, Mario, Trudeau, Louis-Eric, Kamyabiazar, Samaneh, Annabi, Borhane, Robert, Francis, Pelletier, Jerry, El-Kadiry, Abed-El-Hakim, Shammaa, Riam, Rafei, Moutih
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8714858/ https://www.ncbi.nlm.nih.gov/pubmed/35028603 http://dx.doi.org/10.1016/j.xcrm.2021.100455

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