Lupus nephritis and beyond: Kidney-intrinsic genetic risk for antibody deposition

Antibody deposition is a defining pathological feature of multiple kidney diseases including lupus nephritis. In this issue of Cell Reports Medicine, Jiang and colleagues(1) identify a novel genetic risk factor, VANGL1, which predisposes individuals toward antibody deposition via a kidney-intrinsic...

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Detalles Bibliográficos
Autores principales: Chernova, Irene, Craft, Joe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8714907/
https://www.ncbi.nlm.nih.gov/pubmed/35028618
http://dx.doi.org/10.1016/j.xcrm.2021.100479
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author Chernova, Irene
Craft, Joe
author_facet Chernova, Irene
Craft, Joe
author_sort Chernova, Irene
collection PubMed
description Antibody deposition is a defining pathological feature of multiple kidney diseases including lupus nephritis. In this issue of Cell Reports Medicine, Jiang and colleagues(1) identify a novel genetic risk factor, VANGL1, which predisposes individuals toward antibody deposition via a kidney-intrinsic mechanism.
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spelling pubmed-87149072022-01-12 Lupus nephritis and beyond: Kidney-intrinsic genetic risk for antibody deposition Chernova, Irene Craft, Joe Cell Rep Med Preview Antibody deposition is a defining pathological feature of multiple kidney diseases including lupus nephritis. In this issue of Cell Reports Medicine, Jiang and colleagues(1) identify a novel genetic risk factor, VANGL1, which predisposes individuals toward antibody deposition via a kidney-intrinsic mechanism. Elsevier 2021-12-21 /pmc/articles/PMC8714907/ /pubmed/35028618 http://dx.doi.org/10.1016/j.xcrm.2021.100479 Text en © 2021 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Preview
Chernova, Irene
Craft, Joe
Lupus nephritis and beyond: Kidney-intrinsic genetic risk for antibody deposition
title Lupus nephritis and beyond: Kidney-intrinsic genetic risk for antibody deposition
title_full Lupus nephritis and beyond: Kidney-intrinsic genetic risk for antibody deposition
title_fullStr Lupus nephritis and beyond: Kidney-intrinsic genetic risk for antibody deposition
title_full_unstemmed Lupus nephritis and beyond: Kidney-intrinsic genetic risk for antibody deposition
title_short Lupus nephritis and beyond: Kidney-intrinsic genetic risk for antibody deposition
title_sort lupus nephritis and beyond: kidney-intrinsic genetic risk for antibody deposition
topic Preview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8714907/
https://www.ncbi.nlm.nih.gov/pubmed/35028618
http://dx.doi.org/10.1016/j.xcrm.2021.100479
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