Targeted blockade of immune mechanisms inhibit B precursor acute lymphoblastic leukemia cell invasion of the central nervous system

Acute lymphoblastic leukemia (ALL) dissemination to the central nervous system (CNS) is a challenging clinical problem whose underlying mechanisms are poorly understood. Here, we show that primary human ALL samples injected into the femora of immunodeficient mice migrate to the skull and vertebral b...

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Detalles Bibliográficos
Autores principales: Rajakumar, Sujeetha A., Grandal, Ildiko, Minden, Mark D., Hitzler, Johann K., Guidos, Cynthia J., Danska, Jayne S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8714910/
https://www.ncbi.nlm.nih.gov/pubmed/35028611
http://dx.doi.org/10.1016/j.xcrm.2021.100470

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