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Low Expression of YTH Domain-Containing 1 Promotes Microglial M1 Polarization by Reducing the Stability of Sirtuin 1 mRNA

The N6-methyladenosine (m6A) modification is the most abundant posttranscriptional mRNA modification in mammalian cells and is dynamically modulated by a series of “writers,” “erasers,” and “readers.” Studies have shown that m6A affects RNA metabolism in terms of RNA processing, nuclear export, tran...

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Detalles Bibliográficos
Autores principales:	Zhou, Hongxiu, Xu, Zongren, Liao, Xingyun, Tang, Shiyun, Li, Na, Hou, Shengping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8714917/ https://www.ncbi.nlm.nih.gov/pubmed/34975410 http://dx.doi.org/10.3389/fncel.2021.774305

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