Multiomic analysis identifies CPT1A as a potential therapeutic target in platinum-refractory, high-grade serous ovarian cancer

Resistance to platinum compounds is a major determinant of patient survival in high-grade serous ovarian cancer (HGSOC). To understand mechanisms of platinum resistance and identify potential therapeutic targets in resistant HGSOC, we generated a data resource composed of dynamic (±carboplatin) prot...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Dongqing, Chowdhury, Shrabanti, Wang, Hong, Savage, Sara R., Ivey, Richard G., Kennedy, Jacob J., Whiteaker, Jeffrey R., Lin, Chenwei, Hou, Xiaonan, Oberg, Ann L., Larson, Melissa C., Eskandari, Najmeh, Delisi, Davide A., Gentile, Saverio, Huntoon, Catherine J., Voytovich, Uliana J., Shire, Zahra J., Yu, Qing, Gygi, Steven P., Hoofnagle, Andrew N., Herbert, Zachary T., Lorentzen, Travis D., Calinawan, Anna, Karnitz, Larry M., Weroha, S. John, Kaufmann, Scott H., Zhang, Bing, Wang, Pei, Birrer, Michael J., Paulovich, Amanda G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8714940/
https://www.ncbi.nlm.nih.gov/pubmed/35028612
http://dx.doi.org/10.1016/j.xcrm.2021.100471

Ejemplares similares

Ejemplares similares