More fuel for the fire: Gut microbes and toxicity to immune agonist antibodies in cancer

Microbes in the gut impact response, resistance, and toxicity to numerous cancer therapies, though mechanisms remain incompletely understood. Blake et al. provide further evidence that gut microbes promote toxicity to immune-agonistic antibodies, with opportunities to target these in cancer treatmen...

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Detalles Bibliográficos
Autores principales: Chelvanambi, Manoj, Wargo, Jennifer A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715066/
https://www.ncbi.nlm.nih.gov/pubmed/35028621
http://dx.doi.org/10.1016/j.xcrm.2021.100482
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author Chelvanambi, Manoj
Wargo, Jennifer A.
author_facet Chelvanambi, Manoj
Wargo, Jennifer A.
author_sort Chelvanambi, Manoj
collection PubMed
description Microbes in the gut impact response, resistance, and toxicity to numerous cancer therapies, though mechanisms remain incompletely understood. Blake et al. provide further evidence that gut microbes promote toxicity to immune-agonistic antibodies, with opportunities to target these in cancer treatment.(1)
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spelling pubmed-87150662022-01-12 More fuel for the fire: Gut microbes and toxicity to immune agonist antibodies in cancer Chelvanambi, Manoj Wargo, Jennifer A. Cell Rep Med Preview Microbes in the gut impact response, resistance, and toxicity to numerous cancer therapies, though mechanisms remain incompletely understood. Blake et al. provide further evidence that gut microbes promote toxicity to immune-agonistic antibodies, with opportunities to target these in cancer treatment.(1) Elsevier 2021-12-21 /pmc/articles/PMC8715066/ /pubmed/35028621 http://dx.doi.org/10.1016/j.xcrm.2021.100482 Text en © 2021 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Preview
Chelvanambi, Manoj
Wargo, Jennifer A.
More fuel for the fire: Gut microbes and toxicity to immune agonist antibodies in cancer
title More fuel for the fire: Gut microbes and toxicity to immune agonist antibodies in cancer
title_full More fuel for the fire: Gut microbes and toxicity to immune agonist antibodies in cancer
title_fullStr More fuel for the fire: Gut microbes and toxicity to immune agonist antibodies in cancer
title_full_unstemmed More fuel for the fire: Gut microbes and toxicity to immune agonist antibodies in cancer
title_short More fuel for the fire: Gut microbes and toxicity to immune agonist antibodies in cancer
title_sort more fuel for the fire: gut microbes and toxicity to immune agonist antibodies in cancer
topic Preview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715066/
https://www.ncbi.nlm.nih.gov/pubmed/35028621
http://dx.doi.org/10.1016/j.xcrm.2021.100482
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