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Multi-omic analysis in injured humans: Patterns align with outcomes and treatment responses
Trauma is a leading cause of death and morbidity worldwide. Here, we present the analysis of a longitudinal multi-omic dataset comprising clinical, cytokine, endotheliopathy biomarker, lipidome, metabolome, and proteome data from severely injured humans. A “systemic storm” pattern with release of 1,...
Autores principales: | Wu, Junru, Vodovotz, Yoram, Abdelhamid, Sultan, Guyette, Francis X., Yaffe, Michael B., Gruen, Danielle S., Cyr, Anthony, Okonkwo, David O., Kar, Upendra K., Krishnamoorthi, Neha, Voinchet, Robert G., Billiar, Isabel M., Yazer, Mark H., Namas, Rami A., Daley, Brian J., Miller, Richard S., Harbrecht, Brian G., Claridge, Jeffrey A., Phelan, Herbert A., Zuckerbraun, Brian S., Johansson, Pär I., Stensballe, Jakob, Morrissey, James H., Tracy, Russell P., Wisniewski, Stephen R., Neal, Matthew D., Sperry, Jason L., Billiar, Timothy R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715070/ https://www.ncbi.nlm.nih.gov/pubmed/35028617 http://dx.doi.org/10.1016/j.xcrm.2021.100478 |
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