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Caught in a trap: How pre-clinical studies in laboratory mice exaggerate vaccine responses
In a recent issue of Cell Host and Microbe, Fiege and colleagues(1) report that laboratory mice exposed to pathogens from pet-store mice exhibit impaired humoral immunity to influenza vaccination and display gene expression signatures that more authentically reflect human vaccine responses.
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715072/ https://www.ncbi.nlm.nih.gov/pubmed/35028623 http://dx.doi.org/10.1016/j.xcrm.2021.100484 |
| _version_ | 1784624060599107584 |
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| author | Coughlan, Lynda |
| author_facet | Coughlan, Lynda |
| author_sort | Coughlan, Lynda |
| collection | PubMed |
| description | In a recent issue of Cell Host and Microbe, Fiege and colleagues(1) report that laboratory mice exposed to pathogens from pet-store mice exhibit impaired humoral immunity to influenza vaccination and display gene expression signatures that more authentically reflect human vaccine responses. |
| format | Online Article Text |
| id | pubmed-8715072 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2021 |
| publisher | Elsevier |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-87150722022-01-12 Caught in a trap: How pre-clinical studies in laboratory mice exaggerate vaccine responses Coughlan, Lynda Cell Rep Med Spotlight In a recent issue of Cell Host and Microbe, Fiege and colleagues(1) report that laboratory mice exposed to pathogens from pet-store mice exhibit impaired humoral immunity to influenza vaccination and display gene expression signatures that more authentically reflect human vaccine responses. Elsevier 2021-12-21 /pmc/articles/PMC8715072/ /pubmed/35028623 http://dx.doi.org/10.1016/j.xcrm.2021.100484 Text en © 2021 The Author(s) https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
| spellingShingle | Spotlight Coughlan, Lynda Caught in a trap: How pre-clinical studies in laboratory mice exaggerate vaccine responses |
| title | Caught in a trap: How pre-clinical studies in laboratory mice exaggerate vaccine responses |
| title_full | Caught in a trap: How pre-clinical studies in laboratory mice exaggerate vaccine responses |
| title_fullStr | Caught in a trap: How pre-clinical studies in laboratory mice exaggerate vaccine responses |
| title_full_unstemmed | Caught in a trap: How pre-clinical studies in laboratory mice exaggerate vaccine responses |
| title_short | Caught in a trap: How pre-clinical studies in laboratory mice exaggerate vaccine responses |
| title_sort | caught in a trap: how pre-clinical studies in laboratory mice exaggerate vaccine responses |
| topic | Spotlight |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715072/ https://www.ncbi.nlm.nih.gov/pubmed/35028623 http://dx.doi.org/10.1016/j.xcrm.2021.100484 |
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