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Caught in a trap: How pre-clinical studies in laboratory mice exaggerate vaccine responses
In a recent issue of Cell Host and Microbe, Fiege and colleagues(1) report that laboratory mice exposed to pathogens from pet-store mice exhibit impaired humoral immunity to influenza vaccination and display gene expression signatures that more authentically reflect human vaccine responses.
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715072/ https://www.ncbi.nlm.nih.gov/pubmed/35028623 http://dx.doi.org/10.1016/j.xcrm.2021.100484 |