Genome-wide analysis of common and rare variants via multiple knockoffs at biobank scale, with an application to Alzheimer disease genetics

Knockoff-based methods have become increasingly popular due to their enhanced power for locus discovery and their ability to prioritize putative causal variants in a genome-wide analysis. However, because of the substantial computational cost for generating knockoffs, existing knockoff approaches ca...

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Detalles Bibliográficos
Autores principales: He, Zihuai, Le Guen, Yann, Liu, Linxi, Lee, Justin, Ma, Shiyang, Yang, Andrew C., Liu, Xiaoxia, Rutledge, Jarod, Losada, Patricia Moran, Song, Bowen, Belloy, Michael E., Butler, Robert R., Longo, Frank M., Tang, Hua, Mormino, Elizabeth C., Wyss-Coray, Tony, Greicius, Michael D., Ionita-Laza, Iuliana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715147/
https://www.ncbi.nlm.nih.gov/pubmed/34767756
http://dx.doi.org/10.1016/j.ajhg.2021.10.009

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