KDM6A Regulates Cell Plasticity and Pancreatic Cancer Progression by Noncanonical Activin Pathway

BACKGROUND & AIMS: Inactivating mutations of KDM6A, a histone demethylase, were frequently found in pancreatic ductal adenocarcinoma (PDAC). We investigated the role of KDM6A (lysine demethylase 6A) in PDAC development. METHODS: We performed a pancreatic tissue microarray analysis of KDM6A prote...

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Detalles Bibliográficos
Autores principales: Yi, Zhujun, Wei, Shanqiao, Jin, Lin, Jeyarajan, Sivakumar, Yang, Jing, Gu, Yumei, Kim, Hong Sun, Schechter, Shula, Lu, Shuang, Paulsen, Michelle T., Bedi, Karan, Narayanan, Ishwarya Venkata, Ljungman, Mats, Crawford, Howard C., Pasca di Magliano, Marina, Ge, Kai, Dou, Yali, Shi, Jiaqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715196/
https://www.ncbi.nlm.nih.gov/pubmed/34583087
http://dx.doi.org/10.1016/j.jcmgh.2021.09.014

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