Protocol for in utero injection to investigate Zika virus-related fetal microcephaly in mice

Zika virus (ZIKV) is linked to congenital defects including microcephaly. An infection model that can recapitulate most microcephaly-related phenotypes is crucial for understanding ZIKV pathogenesis. Here, we present a protocol to generate ZIKV from an infectious clone through a reverse genetic syst...

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Detalles Bibliográficos
Autores principales: Dong, Shupeng, Xie, Xiaochun, Chen, Yujie, Long, Gang, Liang, Qiming, Zhao, Zhen, Zeng, Jianxiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715324/
https://www.ncbi.nlm.nih.gov/pubmed/35005639
http://dx.doi.org/10.1016/j.xpro.2021.101057

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