Long-term Effectiveness of Adjuvant Treatment With Catechol-O-Methyltransferase or Monoamine Oxidase B Inhibitors Compared With Dopamine Agonists Among Patients With Parkinson Disease Uncontrolled by Levodopa Therapy: The PD MED Randomized Clinical Trial

IMPORTANCE: Many people with Parkinson disease (PD) develop motor complications that are uncontrolled by levodopa dose adjustment. Among these patients, it is uncertain which drug class is more effective as adjuvant therapy. OBJECTIVE: To compare the long-term effects on patient-rated quality of lif...

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Detalles Bibliográficos
Autores principales: Gray, Richard, Patel, Smitaa, Ives, Natalie, Rick, Caroline, Woolley, Rebecca, Muzerengi, Sharon, Gray, Alastair, Jenkinson, Crispin, McIntosh, Emma, Wheatley, Keith, Williams, Adrian, Clarke, C. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2021
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715387/
https://www.ncbi.nlm.nih.gov/pubmed/34962574
http://dx.doi.org/10.1001/jamaneurol.2021.4736

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