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Mutations in the gdpP gene are a clinically relevant mechanism for β-lactam resistance in meticillin-resistant Staphylococcus aureus lacking mec determinants
In Staphylococcus aureus , resistance to β-lactamase stable β-lactam antibiotics is mediated by the penicillinbinding protein 2a, encoded by mecA or by its homologues mecB or mecC. However, a substantial number of meticillin-resistant isolates lack known mec genes and, thus, are called meticillin re...
Autores principales: | Sommer, Anna, Fuchs, Stephan, Layer, Franziska, Schaudinn, Christoph, Weber, Robert E., Richard, Hugues, Erdmann, Mareike B., Laue, Michael, Schuster, Christopher F., Werner, Guido, Strommenger, Birgit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Microbiology Society
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715439/ https://www.ncbi.nlm.nih.gov/pubmed/34486969 http://dx.doi.org/10.1099/mgen.0.000623 |
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