One Omics Approach Does Not Rule Them All: The Metabolome and the Epigenome Join Forces in Haematological Malignancies

Aberrant DNA methylation, dysregulation of chromatin-modifying enzymes, and microRNAs (miRNAs) play a crucial role in haematological malignancies. These epimutations, with an impact on chromatin accessibility and transcriptional output, are often associated with genomic instability and the emergence...

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Detalles Bibliográficos
Autores principales: Kalushkova, Antonia, Nylund, Patrick, Párraga, Alba Atienza, Lennartsson, Andreas, Jernberg-Wiklund, Helena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715477/
https://www.ncbi.nlm.nih.gov/pubmed/34968247
http://dx.doi.org/10.3390/epigenomes5040022

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