Cargando…
FLASH Proton Radiotherapy Spares Normal Epithelial and Mesenchymal Tissues While Preserving Sarcoma Response
In studies of electron and proton radiotherapy, ultrahigh dose rates of FLASH radiotherapy appear to produce fewer toxicities than standard dose rates while maintaining local tumor control. FLASH-proton radiotherapy (F-PRT) brings the spatial advantages of PRT to FLASH dose rates (>40 Gy/second),...
Autores principales: | Velalopoulou, Anastasia, Karagounis, Ilias V., Cramer, Gwendolyn M., Kim, Michele M., Skoufos, Giorgos, Goia, Denisa, Hagan, Sarah, Verginadis, Ioannis I., Shoniyozov, Khayrullo, Chiango, June, Cerullo, Michelle, Varner, Kelley, Yao, Lutian, Qin, Ling, Hatzigeorgiou, Artemis G., Minn, Andy J., Putt, Mary, Lanza, Matthew, Assenmacher, Charles-Antoine, Radaelli, Enrico, Huck, Jennifer, Diffenderfer, Eric, Dong, Lei, Metz, James, Koumenis, Constantinos, Cengel, Keith A., Maity, Amit, Busch, Theresa M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for Cancer Research
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715480/ https://www.ncbi.nlm.nih.gov/pubmed/34321243 http://dx.doi.org/10.1158/0008-5472.CAN-21-1500 |
Ejemplares similares
-
Comparison of FLASH Proton Entrance and the Spread-Out Bragg Peak Dose Regions in the Sparing of Mouse Intestinal Crypts and in a Pancreatic Tumor Model
por: Kim, Michele M., et al.
Publicado: (2021) -
Design and commissioning of an image-guided small animal radiation platform and quality assurance protocol for integrated proton and x-ray radiobiology research
por: Kim, Michele M, et al.
Publicado: (2019) -
3173 A Mouse Model to Study Image-Guided, Radiation-Induced Cardiac Injury and Potential Clinically Targetable Biologic Mediators
por: Dreyfuss, Alexandra, et al.
Publicado: (2019) -
DIANA-microT 2023: including predicted targets of virally encoded miRNAs
por: Tastsoglou, Spyros, et al.
Publicado: (2023) -
A stromal Integrated Stress Response activates perivascular cancer-associated fibroblasts to drive angiogenesis and tumour progression
por: Verginadis, Ioannis I., et al.
Publicado: (2022)