Preparation, toxicity reduction and radiation therapy application of gold nanorods

Gold nanorods (GNRs) have a broad application prospect in biomedical fields because of their unique properties and controllable surface modification. The element aurum (Au) with high atomic number (high-Z) render GNRs ideal radiosensitive materials for radiation therapy and computed tomography (CT)...

Descripción completa

Detalles Bibliográficos
Autores principales: Xie, Lina, Zhang, Xujia, Chu, Chengchao, Dong, Yingqi, Zhang, Tianzi, Li, Xinyue, Liu, Gang, Cai, Wen, Han, Suxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715590/
https://www.ncbi.nlm.nih.gov/pubmed/34963479
http://dx.doi.org/10.1186/s12951-021-01209-4
_version_ 1784624156904521728
author Xie, Lina
Zhang, Xujia
Chu, Chengchao
Dong, Yingqi
Zhang, Tianzi
Li, Xinyue
Liu, Gang
Cai, Wen
Han, Suxia
author_facet Xie, Lina
Zhang, Xujia
Chu, Chengchao
Dong, Yingqi
Zhang, Tianzi
Li, Xinyue
Liu, Gang
Cai, Wen
Han, Suxia
author_sort Xie, Lina
collection PubMed
description Gold nanorods (GNRs) have a broad application prospect in biomedical fields because of their unique properties and controllable surface modification. The element aurum (Au) with high atomic number (high-Z) render GNRs ideal radiosensitive materials for radiation therapy and computed tomography (CT) imaging. Besides, GNRs have the capability of efficiently converting light energy to heat in the near-infrared (NIR) region for photothermal therapy. Although there are more and more researches on GNRs for radiation therapy, how to improve their biocompatibility and how to efficiently utilize them for radiation therapy should be further studied. This review will focuse on the research progress regarding the preparation and toxicity reduction of GNRs, as well as GNRs-mediated radiation therapy. [Image: see text]
format Online
Article
Text
id pubmed-8715590
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-87155902022-01-05 Preparation, toxicity reduction and radiation therapy application of gold nanorods Xie, Lina Zhang, Xujia Chu, Chengchao Dong, Yingqi Zhang, Tianzi Li, Xinyue Liu, Gang Cai, Wen Han, Suxia J Nanobiotechnology Review Gold nanorods (GNRs) have a broad application prospect in biomedical fields because of their unique properties and controllable surface modification. The element aurum (Au) with high atomic number (high-Z) render GNRs ideal radiosensitive materials for radiation therapy and computed tomography (CT) imaging. Besides, GNRs have the capability of efficiently converting light energy to heat in the near-infrared (NIR) region for photothermal therapy. Although there are more and more researches on GNRs for radiation therapy, how to improve their biocompatibility and how to efficiently utilize them for radiation therapy should be further studied. This review will focuse on the research progress regarding the preparation and toxicity reduction of GNRs, as well as GNRs-mediated radiation therapy. [Image: see text] BioMed Central 2021-12-28 /pmc/articles/PMC8715590/ /pubmed/34963479 http://dx.doi.org/10.1186/s12951-021-01209-4 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Review
Xie, Lina
Zhang, Xujia
Chu, Chengchao
Dong, Yingqi
Zhang, Tianzi
Li, Xinyue
Liu, Gang
Cai, Wen
Han, Suxia
Preparation, toxicity reduction and radiation therapy application of gold nanorods
title Preparation, toxicity reduction and radiation therapy application of gold nanorods
title_full Preparation, toxicity reduction and radiation therapy application of gold nanorods
title_fullStr Preparation, toxicity reduction and radiation therapy application of gold nanorods
title_full_unstemmed Preparation, toxicity reduction and radiation therapy application of gold nanorods
title_short Preparation, toxicity reduction and radiation therapy application of gold nanorods
title_sort preparation, toxicity reduction and radiation therapy application of gold nanorods
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715590/
https://www.ncbi.nlm.nih.gov/pubmed/34963479
http://dx.doi.org/10.1186/s12951-021-01209-4
work_keys_str_mv AT xielina preparationtoxicityreductionandradiationtherapyapplicationofgoldnanorods
AT zhangxujia preparationtoxicityreductionandradiationtherapyapplicationofgoldnanorods
AT chuchengchao preparationtoxicityreductionandradiationtherapyapplicationofgoldnanorods
AT dongyingqi preparationtoxicityreductionandradiationtherapyapplicationofgoldnanorods
AT zhangtianzi preparationtoxicityreductionandradiationtherapyapplicationofgoldnanorods
AT lixinyue preparationtoxicityreductionandradiationtherapyapplicationofgoldnanorods
AT liugang preparationtoxicityreductionandradiationtherapyapplicationofgoldnanorods
AT caiwen preparationtoxicityreductionandradiationtherapyapplicationofgoldnanorods
AT hansuxia preparationtoxicityreductionandradiationtherapyapplicationofgoldnanorods

Ejemplares similares