Heterologous production of active form of beta-lytic protease by Bacillus subtilis and improvement of staphylolytic activity by protein engineering

BACKGROUND: Most of the proteases classified into the M23 family in the MEROPS database exhibit staphylolytic activity and have potential as antibacterial agents. The M23 family is further classified into two subfamilies, M23A and M23B. Proteases of the M23A subfamily are thought to lack the capacit...

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Detalles Bibliográficos
Autores principales: Hioki, Takahiro, Yamashita, Daichi, Tohata, Masatoshi, Endo, Keiji, Kawahara, Akihito, Okuda, Mitsuyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715609/
https://www.ncbi.nlm.nih.gov/pubmed/34963446
http://dx.doi.org/10.1186/s12934-021-01724-x

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