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An Investigation for Large Volume, Focal Blood-Brain Barrier Disruption with High-Frequency Pulsed Electric Fields
The treatment of CNS disorders suffers from the inability to deliver large therapeutic agents to the brain parenchyma due to protection from the blood-brain barrier (BBB). Herein, we investigated high-frequency pulsed electric field (HF-PEF) therapy of various pulse widths and interphase delays for...
Autores principales: | Lorenzo, Melvin F., Campelo, Sabrina N., Arroyo, Julio P., Aycock, Kenneth N., Hinckley, Jonathan, Arena, Christopher B., Rossmeisl, John H., Davalos, Rafael V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715747/ https://www.ncbi.nlm.nih.gov/pubmed/34959733 http://dx.doi.org/10.3390/ph14121333 |
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