Bilateral diffuse uveal melanocytic proliferation: Report of a rare ocular paraneoplastic syndrome

Bilateral diffuse uveal melanocytic proliferation is a rare paraneoplastic disorder where bilateral blindness is caused by uveal thickening, serous retinal detachment, and rapid cataract formation. Several different malignancies have been associated with bilateral diffuse uveal melanocytic prolifera...

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Autores principales: Boukari, Mejdi, Braham, Imen Zhioua, Kaouel, Héla, Anane, Maroua, Ammous, Imen, Zhioua, Raja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Societe Tunisienne Des Sciences Medicales 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715793/
https://www.ncbi.nlm.nih.gov/pubmed/33899202
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author Boukari, Mejdi
Braham, Imen Zhioua
Kaouel, Héla
Anane, Maroua
Ammous, Imen
Zhioua, Raja
author_facet Boukari, Mejdi
Braham, Imen Zhioua
Kaouel, Héla
Anane, Maroua
Ammous, Imen
Zhioua, Raja
author_sort Boukari, Mejdi
collection PubMed
description Bilateral diffuse uveal melanocytic proliferation is a rare paraneoplastic disorder where bilateral blindness is caused by uveal thickening, serous retinal detachment, and rapid cataract formation. Several different malignancies have been associated with bilateral diffuse uveal melanocytic proliferation, but ovarian carcinoma in women and lung and pancreatic carcinoma in men are the most common. The underlying mechanism is thought to be related to a an endogenous factor wich regulates the proliferation of uveal melanocytes. We present the case of a 75-year-old man with bilateral diffuse uveal melanocytic proliferation secondary to pulmonary adenocarcinoma.
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spelling pubmed-87157932022-01-19 Bilateral diffuse uveal melanocytic proliferation: Report of a rare ocular paraneoplastic syndrome Boukari, Mejdi Braham, Imen Zhioua Kaouel, Héla Anane, Maroua Ammous, Imen Zhioua, Raja Tunis Med Article Bilateral diffuse uveal melanocytic proliferation is a rare paraneoplastic disorder where bilateral blindness is caused by uveal thickening, serous retinal detachment, and rapid cataract formation. Several different malignancies have been associated with bilateral diffuse uveal melanocytic proliferation, but ovarian carcinoma in women and lung and pancreatic carcinoma in men are the most common. The underlying mechanism is thought to be related to a an endogenous factor wich regulates the proliferation of uveal melanocytes. We present the case of a 75-year-old man with bilateral diffuse uveal melanocytic proliferation secondary to pulmonary adenocarcinoma. Societe Tunisienne Des Sciences Medicales 2021-02 2021-02-01 /pmc/articles/PMC8715793/ /pubmed/33899202 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 Unported License. To view a copy of this license, visit https://creativecommons.org/licenses/by-nc-nd/4.0/
spellingShingle Article
Boukari, Mejdi
Braham, Imen Zhioua
Kaouel, Héla
Anane, Maroua
Ammous, Imen
Zhioua, Raja
Bilateral diffuse uveal melanocytic proliferation: Report of a rare ocular paraneoplastic syndrome
title Bilateral diffuse uveal melanocytic proliferation: Report of a rare ocular paraneoplastic syndrome
title_full Bilateral diffuse uveal melanocytic proliferation: Report of a rare ocular paraneoplastic syndrome
title_fullStr Bilateral diffuse uveal melanocytic proliferation: Report of a rare ocular paraneoplastic syndrome
title_full_unstemmed Bilateral diffuse uveal melanocytic proliferation: Report of a rare ocular paraneoplastic syndrome
title_short Bilateral diffuse uveal melanocytic proliferation: Report of a rare ocular paraneoplastic syndrome
title_sort bilateral diffuse uveal melanocytic proliferation: report of a rare ocular paraneoplastic syndrome
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715793/
https://www.ncbi.nlm.nih.gov/pubmed/33899202
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