Cargando…

Claudin‐2 promotes colorectal cancer growth and metastasis by suppressing NDRG1 transcription

Colorectal cancer (CRC) is one of the most common malignant tumours, with multiple driving factors and biological transitions involved in its development. Claudin‐2 (CLDN2), a well‐defined component of cellular tight junction, has been indicated to associate with CRC progression. However, the functi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wei, Mingtian, Zhang, Yaguang, Yang, Xuyang, Ma, Pingfan, Li, Yan, Wu, Yangping, Chen, Xiangzheng, Deng, Xiangbing, Yang, Tinghan, Mao, Xiaobing, Qiu, Lei, Meng, Wenjian, Zhang, Bo, Wang, Ziqiang, Han, Junhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715829/ https://www.ncbi.nlm.nih.gov/pubmed/34965023 http://dx.doi.org/10.1002/ctm2.667

Ejemplares similares

Malignant ascites-derived exosomes promote proliferation and induce carcinoma-associated fibroblasts transition in peritoneal mesothelial cells
por: Wei, Mingtian, et al.
Publicado: (2017)

Colorectal cancer-derived extracellular vesicles induce liver premetastatic immunosuppressive niche formation to promote tumor early liver metastasis
por: Yang, Xuyang, et al.
Publicado: (2023)

Low-dose capecitabine adjuvant chemotherapy in elderly stage II/III colorectal cancer patients (LC-ACEC): study protocol for a randomized controlled trial
por: He, Yazhou, et al.
Publicado: (2015)

The Key Role of Exosomes on the Pre-metastatic Niche Formation in Tumors
por: Yang, Xuyang, et al.
Publicado: (2021)

DOG1 as a novel antibody-drug conjugate target for the treatment of multiple gastrointestinal tumors and liver metastasis
por: Wu, Yangping, et al.
Publicado: (2023)

Preservation versus non-preservation of left colic artery in colorectal cancer surgery: An updated systematic review and meta-analysis
por: Yang, Xuyang, et al.
Publicado: (2019)

A novel hand-assisted laparoscopic versus conventional laparoscopic right hemicolectomy for right colon cancer: study protocol for a randomized controlled trial
por: Yang, Xuyang, et al.
Publicado: (2017)

Salidroside alleviates cachexia symptoms in mouse models of cancer cachexia via activating mTOR signalling
por: Chen, Xiangzheng, et al.
Publicado: (2016)

The effect of pericolic lymph nodes metastasis beyond 10 cm proximal to the tumor on patients with rectal cancer
por: Yang, Xuyang, et al.
Publicado: (2020)

The effect of BMI on long-term outcome in patients with rectal cancer and establishment of a nomogram prediction model
por: Zhang, Yang, et al.
Publicado: (2023)

The diagnostic value of exosomal circular RNAs in cancer patients: A systematic review and meta‐analysis
por: Zhang, Yang, et al.
Publicado: (2022)

The Role of CXCL12 Axis in Lung Metastasis of Colorectal Cancer
por: Wang, Meng, et al.
Publicado: (2018)

Comprehensive Analysis of Potential Prognostic Values of ANGPTLs in Colorectal Cancer
por: Zhang, Yang, et al.
Publicado: (2022)

Pelvic peritoneum reconstruction using the bladder peritoneum flap in laparoscopic extralevator abdominoperineal excision: A multi-center, prospective single-arm cohort study (IDEAL Phase 2A)
por: Shen, Yu, et al.
Publicado: (2020)

What is the role of lateral lymph node dissection in rectal cancer patients with clinically suspected lateral lymph node metastasis after preoperative chemoradiotherapy? A meta‐analysis and systematic review
por: Yang, Xuyang, et al.
Publicado: (2020)

Impact of XRCC2 Arg188His Polymorphism on Cancer Susceptibility: A Meta-Analysis
por: He, Yazhou, et al.
Publicado: (2014)

Diagnostic performance of various liquid biopsy methods in detecting colorectal cancer: A meta‐analysis
por: Zhu, Yuzhou, et al.
Publicado: (2020)

Do inflammatory markers predict prognosis in patients with synchronous colorectal cancer?
por: He, Wanbin, et al.
Publicado: (2017)

eIF3i promotes colorectal cancer cell survival via augmenting PHGDH translation
por: Zhang, Yaguang, et al.
Publicado: (2023)

Lateral pelvic lymph node dissection after neoadjuvant chemo-radiation for preoperative enlarged lateral nodes in advanced low rectal cancer: study protocol for a randomized controlled trial
por: Wei, Mingtian, et al.
Publicado: (2016)

Survival outcomes of stage I colorectal cancer: development and validation of the ACEPLY model using two prospective cohorts
por: Wu, Qingbin, et al.
Publicado: (2023)

Evaluation of the Prognostic Relevance of Differential Claudin Gene Expression Highlights Claudin-4 as Being Suppressed by TGFβ1 Inhibitor in Colorectal Cancer
por: Yang, Linqi, et al.
Publicado: (2022)

Comparison of the pathological response to 2 or 4 cycles of neoadjuvant CAPOX in II/III rectal cancer patients with low/intermediate risks: study protocol for a prospective, non-inferior, randomized control trial (COPEC trial)
por: Shen, Yu, et al.
Publicado: (2023)

Outcomes of open, laparoscopic, and hand-assisted laparoscopic surgeries in elderly patients with right colon cancers: A case–control study
por: Wei, Mingtian, et al.
Publicado: (2018)

Magnetic Resonance Imaging Evaluation of the Accuracy of Various Lymph Node Staging Criteria in Rectal Cancer: A Systematic Review and Meta-Analysis
por: Zhuang, Zixuan, et al.
Publicado: (2021)

Identification of Hub Genes Related to Liver Metastasis of Colorectal Cancer by Integrative Analysis
por: Liu, Sicheng, et al.
Publicado: (2021)

NDRG3 facilitates colorectal cancer metastasis through activating Src phosphorylation
por: Li, Ting, et al.
Publicado: (2018)

Clinical Diagnostic and Prognostic Potential of NDRG1 and NDRG2 in Hepatocellular Carcinoma Patients
por: Xu, Shaohua, et al.
Publicado: (2022)

The Metastasis Suppressor, N-myc Downregulated Gene 1 (NDRG1), Is a Prognostic Biomarker for Human Colorectal Cancer
por: Mao, Zhihai, et al.
Publicado: (2013)

Targeting CRL4 suppresses chemoresistant ovarian cancer growth by inducing mitophagy
por: Meng, Yang, et al.
Publicado: (2022)

Methylated claudin-11 associated with metastasis and poor survival of colorectal cancer
por: Li, Jinyun, et al.
Publicado: (2017)

Oncogenic MNK signalling regulates the metastasis suppressor NDRG1
por: Tian, Shuye, et al.
Publicado: (2017)

Sequential biphasic changes in claudin1 and claudin4 expression are correlated to colorectal cancer progression and liver metastasis
por: Georges, Rania, et al.
Publicado: (2012)

Claudin-10 overexpression suppresses human clear cell renal cell carcinoma growth and metastasis by regulating ATP5O and causing mitochondrial dysfunction
por: Yang, Wuping, et al.
Publicado: (2022)

NDRG1 suppresses vasculogenic mimicry and tumor aggressiveness in gastric carcinoma
por: Dong, Xueyi, et al.
Publicado: (2019)

First-line cetuximab versus bevacizumab for RAS and BRAF wild-type metastatic colorectal cancer: a systematic review and meta-analysis
por: Zheng, Bobo, et al.
Publicado: (2019)

AKT inhibitor suppresses hyperthermia-induced Ndrg2 phosphorylation in gastric cancer cells
por: Tao, Yurong, et al.
Publicado: (2013)

NDRG1 is expressed in human granulosa cells: An implicative role of NDRG1 in the ovary
por: Nishigaki, Akemi, et al.
Publicado: (2022)

TeachMe: a web-based teaching system for annotating abdominal lymph nodes
por: Chen, Shuaihua, et al.
Publicado: (2022)

NDRG1 enhances the sensitivity of cetuximab by modulating EGFR trafficking in colorectal cancer
por: Yang, Guang, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_lk7d599h9lt11dcer195roqha6