Hormone Receptor Down-Regulation in Metastatic Breast Cancer After Endocrine Therapy Detected in Oophorectomy: A Case Report and Review of Literature

Globally, breast cancer is the most frequently diagnosed malignancy among women; it is also one of the leading causes of cancer mortality among females. The most common sites for metastases are the lungs, bones, liver, and brain. Breast cancer is recognized as one of the most common primary sites of...

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Autores principales: Barron, Marina, Asaad, Amira, Idaewor, Philip, Rasheed, Noreen, Saad Abdalla Al-Zawi, Abdalla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Obstetrics/Gynecology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715835/
https://www.ncbi.nlm.nih.gov/pubmed/34984146
http://dx.doi.org/10.7759/cureus.19994
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author Barron, Marina
Asaad, Amira
Idaewor, Philip
Rasheed, Noreen
Saad Abdalla Al-Zawi, Abdalla
author_facet Barron, Marina
Asaad, Amira
Idaewor, Philip
Rasheed, Noreen
Saad Abdalla Al-Zawi, Abdalla
author_sort Barron, Marina
collection PubMed
description Globally, breast cancer is the most frequently diagnosed malignancy among women; it is also one of the leading causes of cancer mortality among females. The most common sites for metastases are the lungs, bones, liver, and brain. Breast cancer is recognized as one of the most common primary sites of metastatic lesions in the ovaries and is often associated with multiple extra-ovarian metastases. Here, we report a case of occult breast cancer metastases to the ovaries with a down-regulated hormonal immunohistochemistry profile after endocrine therapy, encountered incidentally after oophorectomy.
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spelling pubmed-87158352022-01-03 Hormone Receptor Down-Regulation in Metastatic Breast Cancer After Endocrine Therapy Detected in Oophorectomy: A Case Report and Review of Literature Barron, Marina Asaad, Amira Idaewor, Philip Rasheed, Noreen Saad Abdalla Al-Zawi, Abdalla Cureus Obstetrics/Gynecology Globally, breast cancer is the most frequently diagnosed malignancy among women; it is also one of the leading causes of cancer mortality among females. The most common sites for metastases are the lungs, bones, liver, and brain. Breast cancer is recognized as one of the most common primary sites of metastatic lesions in the ovaries and is often associated with multiple extra-ovarian metastases. Here, we report a case of occult breast cancer metastases to the ovaries with a down-regulated hormonal immunohistochemistry profile after endocrine therapy, encountered incidentally after oophorectomy. Cureus 2021-11-29 /pmc/articles/PMC8715835/ /pubmed/34984146 http://dx.doi.org/10.7759/cureus.19994 Text en Copyright © 2021, Barron et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Obstetrics/Gynecology
Barron, Marina
Asaad, Amira
Idaewor, Philip
Rasheed, Noreen
Saad Abdalla Al-Zawi, Abdalla
Hormone Receptor Down-Regulation in Metastatic Breast Cancer After Endocrine Therapy Detected in Oophorectomy: A Case Report and Review of Literature
title Hormone Receptor Down-Regulation in Metastatic Breast Cancer After Endocrine Therapy Detected in Oophorectomy: A Case Report and Review of Literature
title_full Hormone Receptor Down-Regulation in Metastatic Breast Cancer After Endocrine Therapy Detected in Oophorectomy: A Case Report and Review of Literature
title_fullStr Hormone Receptor Down-Regulation in Metastatic Breast Cancer After Endocrine Therapy Detected in Oophorectomy: A Case Report and Review of Literature
title_full_unstemmed Hormone Receptor Down-Regulation in Metastatic Breast Cancer After Endocrine Therapy Detected in Oophorectomy: A Case Report and Review of Literature
title_short Hormone Receptor Down-Regulation in Metastatic Breast Cancer After Endocrine Therapy Detected in Oophorectomy: A Case Report and Review of Literature
title_sort hormone receptor down-regulation in metastatic breast cancer after endocrine therapy detected in oophorectomy: a case report and review of literature
topic Obstetrics/Gynecology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715835/
https://www.ncbi.nlm.nih.gov/pubmed/34984146
http://dx.doi.org/10.7759/cureus.19994
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