HIV-1 Vpr protein upregulates microRNA-210-5p expression to induce G(2) arrest by targeting TGIF2

MicroRNAs (miRNAs) are important molecules that mediate virus-host interactions, mainly by regulating gene expression via gene silencing. Here, we demonstrated that HIV-1 infection upregulated miR-210-5p in HIV-1-inoculated cell lines and in the serum of HIV-1-infected individuals. Luciferase report...

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Detalles Bibliográficos
Autores principales: Qiao, Jialu, Peng, Qian, Qian, Feng, You, Qiang, Feng, Lingyan, Hu, Song, Liu, Wei, Huang, Lixia, Shu, Xiji, Sun, Binlian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8716043/
https://www.ncbi.nlm.nih.gov/pubmed/34965271
http://dx.doi.org/10.1371/journal.pone.0261971

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