Intranasal immunization with a Middle East respiratory syndrome-coronavirus antigen conjugated to the M-cell targeting ligand Co4B enhances antigen-specific mucosal and systemic immunity and protects against infection

Middle East respiratory syndrome (MERS) is a threat to public health worldwide. A vaccine against the causative agent of MERS, MERS-coronavirus (MERS-CoV), is urgently needed. We previously identified a peptide ligand, Co4B, which can enhance antigen (Ag) delivery to the nasal mucosa and promote Ag-...

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Detalles Bibliográficos
Autores principales: Yang, Ye Lin, Kim, Ju, Jeong, Yongsu, Jang, Yong-Suk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8716170/
https://www.ncbi.nlm.nih.gov/pubmed/34991928
http://dx.doi.org/10.1016/j.vaccine.2021.12.057

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8716170/
https://www.ncbi.nlm.nih.gov/pubmed/34991928
http://dx.doi.org/10.1016/j.vaccine.2021.12.057

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