Imaging of anthrax intoxication in mice reveals shared and individual functions of surface receptors CMG-2 and TEM-8 in cellular toxin entry

Bacillus anthracis lethal toxin and edema toxin are binary toxins that consist of a common cell-binding moiety, protective antigen (PA), and the enzymatic moieties, lethal factor (LF) and edema factor (EF). PA binds to either of two receptors, capillary morphogenesis protein-2 (CMG-2) or tumor endot...

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Detalles Bibliográficos
Autores principales: Merritt, Carly, Chun, Elizabeth M., Fattah, Rasem J., Silva, Lakmali M., Ma, Quinn Q., Moayeri, Mahtab, Paliga, Dennis, Neumann, Sebastian, Heumann, Rolf, Leppla, Stephen H., Bugge, Thomas H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8716333/
https://www.ncbi.nlm.nih.gov/pubmed/34871548
http://dx.doi.org/10.1016/j.jbc.2021.101467

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