Soluble Receptor Isoform of IFN-Beta (sIFNAR2) in Multiple Sclerosis Patients and Their Association With the Clinical Response to IFN-Beta Treatment

PURPOSE: Interferon beta receptor 2 subunit (IFNAR2) can be produced as a transmembrane protein, but also as a soluble form (sIFNAR2) generated by alternative splicing or proteolytic cleavage, which has both agonist and antagonist activities for IFN-β. However, its role regarding the clinical respon...

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Detalles Bibliográficos
Autores principales: Aliaga-Gaspar, Pablo, Hurtado-Guerrero, Isaac, Ciano-Petersen, Nicolas Lundahl, Urbaneja, Patricia, Brichette-Mieg, Isabel, Reyes, Virginia, Rodriguez-Bada, Jose Luis, Alvarez-Lafuente, Roberto, Arroyo, Rafael, Quintana, Ester, Ramió-Torrentà, Lluis, Alonso, Ana, Leyva, Laura, Fernández, Oscar, Oliver-Martos, Begoña
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8716373/
https://www.ncbi.nlm.nih.gov/pubmed/34975865
http://dx.doi.org/10.3389/fimmu.2021.778204

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8716373/
https://www.ncbi.nlm.nih.gov/pubmed/34975865
http://dx.doi.org/10.3389/fimmu.2021.778204

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