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Radiolabeled Monoclonal Antibody Against Colony-Stimulating Factor 1 Receptor Specifically Distributes to the Spleen and Liver in Immunocompetent Mice

Macrophages can promote tumor development. Preclinically, targeting macrophages by colony-stimulating factor 1 (CSF1)/CSF1 receptor (CSF1R) monoclonal antibodies (mAbs) enhances conventional therapeutics in combination treatments. The physiological distribution and tumor uptake of CSF1R mAbs are unk...

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Detalles Bibliográficos
Autores principales:	Waaijer, Stijn J. H., Suurs, Frans V., Hau, Cheei-Sing, Vrijland, Kim, de Visser, Karin E., de Groot, Derk Jan A., de Vries, Elisabeth G. E., Lub-de Hooge, Marjolijn N., Schröder, Carolina P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8716378/ https://www.ncbi.nlm.nih.gov/pubmed/34976826 http://dx.doi.org/10.3389/fonc.2021.786191

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