Merbromin is a mixed-type inhibitor of 3-chyomotrypsin like protease of SARS-CoV-2

3-chyomotrypsin like protease (3CLpro) has been considered as a promising target for developing anti-SARS-CoV-2 drugs. Herein, about 6000 compounds were analyzed by high-throughput screening using enzyme activity model, and Merbromin, an antibacterial agent, was identified as a potent inhibitor of 3...

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Detalles Bibliográficos
Autores principales: Chen, Junjie, Zhang, Yaya, Zeng, Dequan, Zhang, Bingchang, Ye, Xiaohong, Zeng, Zhiping, Zhang, Xiao-kun, Wang, Zhanxiang, Zhou, Hu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8716398/
https://www.ncbi.nlm.nih.gov/pubmed/35007835
http://dx.doi.org/10.1016/j.bbrc.2021.12.108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8716398/
https://www.ncbi.nlm.nih.gov/pubmed/35007835
http://dx.doi.org/10.1016/j.bbrc.2021.12.108

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