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Thalamic reticular nucleus impairments and abnormal prefrontal control of dopamine system in a developmental model of schizophrenia: prevention by N-acetylcysteine

Recent evidence showed thalamic abnormalities in schizophrenia involving disruptions to the parvalbumin neurons in the thalamic reticular nucleus (TRN). However, their functional consequences, as well as a potential linkage to oxidative stress, are unclear. The TRN is posited to gate prefrontal cont...

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Detalles Bibliográficos
Autores principales: Zhu, Xiyu, Cabungcal, Jan-Harry, Cuenod, Michel, Uliana, Daniela L., Do, Kim Q., Grace, Anthony A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8716611/
https://www.ncbi.nlm.nih.gov/pubmed/34193975
http://dx.doi.org/10.1038/s41380-021-01198-8